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| 1 | 2 | 3 | 4 | T | |
| San Francisco 49ers | 0 | 3 | 3 | 3 | 9 |
| Chicago Bears | 0 | 7 | 0 | 10 | 17 |
| SFO | CHI | |
| 1st Downs | 9 | 12 |
| Total Yards | 161 | 239 |
| Passing | ||
| Yards | 28 | 67 |
| Comp-Att-Int | 1-13-1 | 8-14-1 |
| Yards Per Pass | 2.2 | 4.8 |
| Sacked-Yards Lost | 0-0 | 0-0 |
| Rushing | ||
| Yards | 133 | 172 |
| Attempts | 46 | 40 |
| Average | 2.9 | 4.3 |
| Turnovers | ||
| Interceptions | 1 | 1 |
| Fumbles-Lost | 3-1 | 5-3 |
| Punting | ||
| Punts | 7 | 5 |
| Yards | 283 | 265 |
| Yards Per Punt | 40.4 | 53.0 |
| Penalties | ||
| Penalties | 10 | 5 |
| Yards | 80 | 34 |
| Possession | ||
| Time of Possession | 31:06 | 28:54 |
| PASSING | |||||||||||
| San Francisco | CMP | ATT | PCT | YDS | LNG | YPA | TD | INT | SCK | LOSS | RAT |
| Cody Pickett | 1 | 13 | 7.7 | 28 | 28 | 2.15 | 0 | 1 | 0 | 0 | 7.5 |
| Chicago | CMP | ATT | PCT | YDS | LNG | YPA | TD | INT | SCK | LOSS | RAT |
| Kyle Orton | 8 | 13 | 61.5 | 67 | 31 | 5.15 | 0 | 1 | 0 | 0 | 42.8 |
| Brad Maynard | 0 | 1 | 0.0 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 39.6 |
| RUSHING | |||||||||||
| San Francisco | ATT | YDS | AVG | LNG | TD | ||||||
| Kevan Barlow | 25 | 63 | 2.5 | 17 | 0 | ||||||
| Frank Gore | 14 | 55 | 3.9 | 19 | 0 | ||||||
| Cody Pickett | 6 | 15 | 2.5 | 12 | 0 | ||||||
| Terry Jackson | 1 | 0 | 0.0 | 0 | 0 | ||||||
| Chicago | ATT | YDS | AVG | LNG | TD | ||||||
| Adrian Peterson | 24 | 120 | 5.0 | 34 | 1 | ||||||
| Cedric Benson | 12 | 50 | 4.2 | 18 | 0 | ||||||
| Bryan Johnson | 1 | 5 | 5.0 | 5 | 0 | ||||||
| Kyle Orton | 3 | -3 | -1.0 | 0 | 0 | ||||||
| RECEIVING | |||||||||||
| San Francisco | REC | YDS | AVG | LNG | TD | ||||||
| Brandon Lloyd | 1 | 28 | 28.0 | 28 | 0 | ||||||
| Chicago | REC | YDS | AVG | LNG | TD | ||||||
| Desmond Clark | 2 | 43 | 21.5 | 31 | 0 | ||||||
| Bobby Wade | 1 | 11 | 11.0 | 11 | 0 | ||||||
| Justin Gage | 1 | 6 | 6.0 | 6 | 0 | ||||||
| Muhsin Muhammad | 1 | 3 | 3.0 | 3 | 0 | ||||||
| Bryan Johnson | 2 | 2 | 1.0 | 2 | 0 | ||||||
| Jason Mckie | 1 | 2 | 2.0 | 2 | 0 | ||||||
| KICK/PUNT RETURNS | |||||||||||
| San Francisco | KR | YDS | AVG | LNG | TD | PR | YDS | AVG | LNG | TD | |
| Rasheed Marshall | 1 | 16 | 16.0 | 16 | 0 | 2 | 0 | 0.0 | 0 | 0 | |
| Jason Mcaddley | 2 | 30 | 15.0 | 15 | 0 | 0 | 0 | 0.0 | 0 | 0 | |
| Chicago | KR | YDS | AVG | LNG | TD | PR | YDS | AVG | LNG | TD | |
| Bobby Wade | 0 | 0 | 0.0 | 0 | 0 | 4 | 31 | 7.8 | 17 | 0 | |
| Jerry Azumah | 4 | 83 | 20.8 | 22 | 0 | 0 | 0 | 0.0 | 0 | 0 | |
| PUNTING | |||||||||||
| San Francisco | NUM | YDS | AVG | LNG | TB | IN20 | BLK | ||||
| Andy Lee | 7 | 283 | 40.4 | 44 | 0 | 1 | 0 | ||||
| Chicago | NUM | YDS | AVG | LNG | TB | IN20 | BLK | ||||
| Brad Maynard | 5 | 189 | 37.8 | 45 | 1 | 1 | 0 | ||||
| DEFENSE | |||||||||||
| San Francisco | SK | YDS | INT | YDS | LNG | TD | |||||
| Shawntae Spencer | 0 | 0 | 1 | 0 | 0 | 0 | |||||
| Chicago | SK | YDS | INT | YDS | LNG | TD | |||||
| Mike Brown | 0 | 0 | 1 | 3 | 3 | 0 | |||||
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