Record: 7 - 9 (pythagorean: 8 - 8, .502)
Coaching: Gunther Cunningham 7 - 9
2000 Pro Bowl Players: QB - Elvis Grbac TE - Tony Gonzalez OG - Will Shields
| Round - Pick (Overall Pick) 1-21 (21) - Sylvester Morris, Jackson State, WR 2-23 (54) - William Bartee, Oklahoma, DB 3-23 (85) - Gregory Wesley, Arkansas-Pine Bluff, DB 4-21 (115) - Frank Moreau, Louisville, RB 5-24 (153) - Dante Hall, Texas A&M, RB 5-33 (162) - Patrick Dennis, Louisiana-Monroe, DB 6-22 (188) - Darnell Alford, Boston College, G 7-2 (208) - Desmond Kitchings, Furman, WR
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