Record: 12 - 4 (pythagorean: 11 - 5, .717)
Coaching: Forrest Gregg 12 - 4 (playoffs:2 - 1)
1981 Pro Bowl Players: QB - Ken Anderson FB - Pete Johnson WR - Cris Collinsworth OT - Anthony Munoz P - Pat McInally
| Round - Pick (Overall Pick) 1-10 (10) - David Verser, Kansas, WR 2-9 (37) - Cris Collinsworth, Florida, WR 3-8 (64) - John Simmons, Southern Methodist, DB 4-10 (93) - Guy Frazier, Wyoming, LB 5-9 (120) - Benjie Pryor, Pittsburgh, TE 6-8 (146) - Rex Robinson, Georgia, K 7-10 (176) - Jeff Schuh, Minnesota, LB 8-9 (202) - Bobby Kemp, Fullerton State, DB 9-8 (229) - Jim Hannula, Northern Illinois, T 9-9 (230) - Samoa Samoa, Washington State, RB 10-10 (258) - Hubert Simpson, Tennessee, RB 11-9 (285) - Robert Jackson, Central Michigan, DB 12-8 (312) - Mark O'Connell, Ball State, QB
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